Since its first publication in 1991, New Flora of the British Isles has become established as the standard work on the identification of the wild vascular plants of the British Isles. The Flora remains unique in many features, including its full coverage of all British wild plants, its user-friendly organisation, and its specially compiled keys and descriptions. This new edition includes the addition of more than 160 species, so that 4,800 taxa are now covered in varying degrees of detail. It also incorporates the new molecular system of classification based on DNA sequences. Furthermore, it includes 1600 species illustrations, rewritten distributions and an overhaul of the designation of degrees of rarity, with the introduction of a third, less rare, category. These revisions should ensure that this third edition remains the essential reference source for all taxonomists, ecologists, conservationists, plant hunters and biogeographers, whether they be researchers, teachers, students or amateurs.
Pubpsher: Karger Medical and Scientific Publishers
Hundreds of bacterial species make up human gut flora. The intestine has at least 400 different species of bacteria totaling over 1012 organisms. Of these, 99% are anaerobic bacteria. The gastrointestinal tract is then exposed to countless numbers of bacterial species and foreign antigens and has embedded a unique and complex network of immunological and non-immunological mechanisms to protect the host from potentially harmful pathogens. Healthy individuals are generally tolerant to their own microbiota, but such tolerance is impaired in patients with both organic and functional gastrointestinal diseases. The advancement of the knowledge on microbial-gut interactions in health and disease has allowed a more pathophysiologically-oriented approach to several challenging clinical conditions. There are currently two ways to manipulate enteric flora. Antibiotics can selectively decrease tissue invasion and eliminate aggressive bacterial species or globally decrease luminal and mucosal bacterial concentrations, depending on their spectrum of activity. Alternatively, administration of beneficial bacterial species (probiotics), poorly absorbed dietary oligosaccharides (prebiotics), or combined probiotics and prebiotics (synbiotics) can restore a predominance of beneficial commensal flora. These two therapeutic approaches are not, of course, mutually exclusive. Rifaximin, a poorly absorbed antibiotic targeted at the gastrointestinal tract, has been long used in Italy for the treatment of infectious diarrhea in both adults and children. During the past few years the appreciation of the pathogenic role of gut bacteria in several organic and functional gastrointestinal diseases has increasingly broadened its clinical use, which now covers hepatic encephalopathy, small intestine bacterial overgrowth, inflammatory bowel disease and colonic diverticular disease. Other potential clinical indications are being explored and look promising.